Axial spondyloarthritis (AxSpA) encompasses a group of inflammatory arthritis conditions primarily impacting the spine, though other joints and even organs can be involved. We invite you to discover more about this range of conditions, their diagnosis and treatment options, and ways you can manage them effectively.
Living with axial spondyloarthritis (AxSpA) presents daily hurdles. There are two main types: radiographic axSpA, also known as ankylosing spondylitis, visible on X-rays due to damage to the sacroiliac joints and spine, and nonradiographic axSpA (nr-axSpA) which might not show on X-rays but can be detected through MRIs. We're here to guide you with expert advice, resources, and support to navigate through your AxSpA journey and alleviate its symptoms.
When you think of psoriasis, you probably picture those red, flaky skin patches that can cause discomfort and self-consciousness. But what if we told you that psoriasis doesn’t just affect your skin—it can impact your joints too? In fact, up to 25% of people with psoriasis experience joint pain, and for some, that pain turns into a more serious condition known as psoriatic arthritis (PsA).
It’s a connection that surprises many, but researchers are actively studying it. And the results could transform how we approach psoriasis and arthritis, helping people live healthier, pain-free lives.
While psoriasis primarily affects the skin, psoriatic arthritis (PsA) is a type of inflammatory arthritis that impacts the joints. It can cause swelling, stiffness, and pain, which can be just as uncomfortable as the skin symptoms of psoriasis, if not more. What’s more, PsA can develop silently in some people, without obvious skin symptoms beforehand.
Here’s where things get interesting: about one-third of people with psoriasis may eventually develop PsA. This means that many people who currently deal with psoriasis are at risk of future joint pain—but experts are working hard to figure out why this happens and how to stop it before it starts.
In an exciting effort to better understand the link between psoriasis and joint pain, researchers from Oxford University, University College Dublin, and other leading institutions are conducting a massive international study called the HIPPOCRATES Project. The goal? To uncover early warning signs of PsA and find ways to prevent it from developing in people with psoriasis.
So far, the project has been tracking nearly 3,000 psoriasis patients, with 25% of them already experiencing joint symptoms. But this is just the beginning. Over the course of three years, the study will follow these patients, gathering insights into when and why PsA appears—and how it can be stopped.
What makes the HIPPOCRATES Project so groundbreaking is the scope and the approach. Researchers are collecting detailed health information from participants through online questionnaires and even using finger-prick blood samples that people can send in by mail. This allows patients to participate from home, no matter where they live, and ensures that researchers gather a large, diverse pool of data.
The project plans to recruit 25,000 people with psoriasis across 12 European countries, giving scientists an unprecedented amount of data to analyze. This data could lead to the discovery of key risk factors that predict who will develop PsA, opening the door to early interventions.
The ultimate goal of this study is to find out if we can prevent psoriatic arthritis from developing in the first place. And while there’s no magic pill just yet, researchers are exploring a variety of lifestyle interventions that could help. These include things like:
Regular exercise to keep joints healthy
Stress management techniques to reduce inflammation
Dietary adjustments to support overall well-being
The idea is that by identifying high-risk individuals early, we can recommend simple changes that might keep arthritis at bay and improve quality of life.
Psoriatic arthritis can be life-altering. It doesn’t just cause joint pain—it can also affect mobility and lead to long-term joint damage if left untreated. That’s why the HIPPOCRATES Project is such an important step forward in our understanding of psoriasis and arthritis.
By focusing on early detection and prevention, this research could dramatically change how we treat people with psoriasis, giving them tools to manage their skin and joint health long before PsA develops. Plus, with so many patients involved from different countries, the findings are likely to have a wide-reaching impact.
As the HIPPOCRATES Project continues to unfold, we’re hopeful that its discoveries will lead to better treatments and even preventative measures for PsA. And at the American Arthritis Foundation, we’ll be watching closely to bring you the latest updates on this groundbreaking research.
If you or someone you know is living with psoriasis, staying informed about this connection between skin and joint health is key. Whether through lifestyle changes or new treatments on the horizon, there are steps you can take to protect your joints and improve your overall well-being.
Stay tuned for more on the link between psoriasis and joint health—and follow us for the latest in arthritis research, treatment options, and wellness tips!
Do you have psoriasis or PsA? We’d love to hear your story! Share your experiences with us in the comments below and let’s keep the conversation going about how we can make life with psoriasis and joint pain easier for everyone.
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